Does the general mantra then hold true in your opinion, use the heaviest bullet for subsonic loads.
I have found this to be untrue unless the barrel is changed for subsonic - heavy bullets.
Provided you stay away from the transonic zone, yes. Anything faster than 950fps you take your chances.
The transsonic zone gave me trouble with my .22 and standard ammunition. For some reason, standard ammunition deviated from 940fps up to 1200fps, especially on hot days. It gave erratic groupings - up to two flyers for every five shots.
After I changed to supersonic (high velocity) and subsonic ammunition, the groupings became more consistent.
When I loaded 173gr LRN for my 308, I stuck to 800fps to say clear from the transsonic zone.
For some reason, the accuracy is not very good yet. I still get flyers now and then.
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You having erratic ignition, I found my subsonics to be stupid accurate. 800 fps is just to slow, here on the coast we stay at 1000 - 1040, even the late 900+ fps. Below this funny things seem to happen.
Also, get a proper over powder wad, use quite a bit of toilet paper or cotton wool even a sheet of paper cut in a circle pushed in with a pencil, then kapok, I put a lot in,almost a compressed load, just get better ignition.
I must buy another sedate caliber rifle and play again.